Description

5-Bromo-3-Chloro-2-Methoxyisonicotinaldehyde is a high-purity, multi-functional heterocyclic aldehyde building block essential for advanced organic synthesis. Its unique halogenated and methoxylated pyridine core makes it a critical intermediate for constructing complex molecular architectures with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides due to its reactive aldehyde and halogen substituents.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized chelating ligands and organocatalysts in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials.
• Chemical Biology Probes: Useful for creating tagged molecules and activity-based probes for studying biological systems.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific halogenated pyridine derivatives.

Basic Information

Item	Details
Product Name	5-Bromo-3-Chloro-2-Methoxyisonicotinaldehyde
CAS No.	1224604-20-9
Molecular Formula	C8H5BrClNO2
Molecular Weight	264.49 g/mol
Synonyms	5-Bromo-3-chloro-2-methoxypyridine-4-carbaldehyde; 4-Formyl-5-bromo-3-chloro-2-methoxypyridine; 2-Methoxy-5-bromo-3-chloropyridine-4-carboxaldehyde; 5-Bromo-3-chloro-2-methoxy-4-pyridinecarboxaldehyde; 1224604-20-9; 5-Br-3-Cl-2-MeO-isonicotinaldehyde
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-3-Chloro-2-Methoxyisonicotinaldehyde is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure high purity and lot-to-lot consistency to meet the stringent requirements of research and development. A detailed Certificate of Analysis (COA) providing purity (typically by HPLC), identity confirmation, and impurity profile is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.