Description

Methyl 5,5,5-Trifluoro-4-(4-Fluorophenylamino)Pentanoate is a high-value fluorinated building block and advanced pharmaceutical intermediate. Its molecular structure, featuring both trifluoromethyl and fluorophenylamino groups, makes it a critical synthon for introducing lipophilicity and metabolic stability into target molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active ingredients, particularly in therapeutic areas requiring fine-tuned physicochemical properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in medicinal chemistry programs targeting CNS disorders, oncology, and inflammatory diseases.
• Agrochemical Research: Used in the development of advanced pesticides and herbicides, where the fluorine atoms enhance biological activity and environmental persistence.
• Fluorinated Compound Synthesis: Serves as a versatile precursor for creating more complex fluorinated organic molecules in specialty chemical manufacturing.
• Material Science: Potential monomer or modifier in the research of fluorinated polymers with unique surface properties, chemical resistance, or optical characteristics.
• Academic & R&D: Employed in university and corporate laboratories for methodological studies in organic synthesis, particularly in reactions involving fluorinated amines and esters.

Basic Information

Product Name	Methyl 5,5,5-Trifluoro-4-(4-Fluorophenylamino)Pentanoate
CAS No.	1224599-57-8
Molecular Formula	C12H13F4NO2
Molecular Weight	279.23 g/mol
Synonyms	4-(4-Fluorophenylamino)-5,5,5-trifluoropentanoic acid methyl ester; Methyl 4-[(4-fluorophenyl)amino]-5,5,5-trifluoropentanoate; 5,5,5-Trifluoro-4-(4-fluorophenylamino)pentanoic acid methyl ester; 1224599-57-8; 4-(p-Fluoroanilino)-5,5,5-trifluoropentanoic acid methyl ester; Methyl 5,5,5-trifluoro-4-(p-fluorophenylamino)pentanoate; Pentanoic acid, 5,5,5-trifluoro-4-[(4-fluorophenyl)amino]-, methyl ester
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system to support our clients in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.