Description

2-(Azidomethyl)Benzeneboronic Acid Pinacol Ester, 95% is a specialized bifunctional organic building block that combines a boronic ester group with an azide moiety. This unique structure makes it a highly valuable intermediate for click chemistry and cross-coupling reactions, enabling the modular synthesis of complex molecules. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for applications in drug discovery, bioconjugation, and polymer functionalization.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling and azide-alkyne cycloaddition (CuAAC) reactions.
• Bioconjugation & Probe Development: Used for labeling biomolecules, creating antibody-drug conjugates (ADCs), and developing diagnostic probes due to its orthogonal reactivity.
• Materials Science & Polymer Chemistry: Enables the functionalization of polymers and surfaces, contributing to the development of smart materials and functional coatings.
• Agrochemical Research: Serves as a building block for creating new crop protection agents and herbicides with targeted modes of action.
• Chemical Biology & Library Synthesis: Facilitates the rapid assembly of diverse compound libraries for high-throughput screening in drug discovery campaigns.
• Ligand & Catalyst Development: Employed in the design and synthesis of novel ligands and organocatalysts for asymmetric synthesis.

Basic Information

Product Name	2-(Azidomethyl)Benzeneboronic Acid Pinacol Ester, 95%
CAS No.	1223598-41-1
Molecular Formula	C₁₃H₁₈BN₃O₂
Molecular Weight	259.11 g/mol
Synonyms	2-(Azidomethyl)phenylboronic acid pinacol ester; (2-(Azidomethyl)phenyl)boronic acid pinacol ester; 2-(Azidomethyl)benzeneboronic acid, pinacol ester; Azidomethylphenylboronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[2-(azidomethyl)phenyl]-4,4,5,5-tetramethyl-; B-[2-(Azidomethyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our 2-(Azidomethyl)Benzeneboronic Acid Pinacol Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure a consistent purity of 95% (minimum) and identity. Certificates of Analysis (COA) with full analytical data are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to the light-sensitive nature of the compound, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.