Description

Dibenzyl-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzyl]-Amine is a specialized organoboron building block featuring a protected boronic ester group and a tertiary amine functionality. This compound is of significant value in modern synthetic chemistry, particularly in cross-coupling reactions like the Suzuki-Miyaura reaction, where it serves as a key intermediate for constructing complex molecular architectures. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring complex aryl-amine structures.
• Material Science Research: Serves as a monomer or precursor in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and bioconjugates for studying biological processes and target engagement.
• Ligand & Catalyst Development: Acts as a precursor for synthesizing novel ligands and catalysts used in asymmetric synthesis and other catalytic processes.
• Academic & Contract Research: A valuable reagent for methodology development and complex molecule synthesis in academic and industrial R&D laboratories.

Basic Information

Item	Detail
Product Name	Dibenzyl-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzyl]-Amine
CAS No.	1221824-21-0
Molecular Formula	C28H34BNO2
Molecular Weight	427.39 g/mol
Synonyms	4-((Dibenzylamino)methyl)phenylboronic acid pinacol ester; [4-(Dibenzylaminomethyl)phenyl]boronic acid pinacol ester; N,N-Dibenzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenemethanamine; 2-[4-[(Dibenzylamino)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Dibenzyl(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)amine
EINECS	Contact for details

Quality Control

Our Dibenzyl-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Benzyl]-Amine is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and decomposition. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.