Description

1-Bromo-3-Isobutoxy-5-(Trifluoromethoxy)Benzene is a high-purity, advanced organic intermediate featuring a strategically functionalized benzene ring. This compound is valued for its unique combination of bromo, alkoxy, and trifluoromethoxy substituents, which are critical for modifying the electronic and steric properties of target molecules. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors for OLEDs, due to its electron-withdrawing characteristics.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	1-Bromo-3-Isobutoxy-5-(Trifluoromethoxy)Benzene
CAS No.	1221793-64-1
Molecular Formula	C11H12BrF3O2
Molecular Weight	313.11 g/mol
Synonyms	3-Bromo-1-isobutoxy-5-(trifluoromethoxy)benzene; 1-Bromo-3-(2-methylpropoxy)-5-(trifluoromethoxy)benzene; Benzene, 1-bromo-3-isobutoxy-5-(trifluoromethoxy)-; 5-Bromo-1-isobutoxy-3-(trifluoromethoxy)benzene (isomer); AI3-72731
EINECS	Contact for details

Quality Control

Every batch of 1-Bromo-3-Isobutoxy-5-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency meet the exacting standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible materials. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.