Description

2-Bromo-4-Fluorostyrene is a versatile halogenated styrene derivative serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic placement of bromine and fluorine atoms on the aromatic ring, which enables selective functionalization and facilitates the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing novel active ingredients and specialty polymers.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in creating novel pesticides and herbicides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Monomer for the production of specialty fluorinated polymers with unique surface properties, chemical resistance, or optical characteristics.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic display and lighting applications.
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for palladium-catalyzed reactions like Suzuki, Heck, and Sonogashira couplings.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and reaction pathways.

Basic Information

Product Name	2-Bromo-4-Fluorostyrene
CAS No.	1221684-51-0
Molecular Formula	C8H6BrF
Molecular Weight	201.04 g/mol
Synonyms	1-Bromo-2-(2-fluoroethenyl)benzene; 2-Bromo-1-fluoro-4-vinylbenzene; 4-Fluoro-2-bromostyrene; (2-Bromo-4-fluorophenyl)ethene; 2-Bromo-4-fluorostyrol; Vinyl-2-bromo-4-fluorobenzene; β-(2-Bromo-4-fluorophenyl)ethylene
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Fluorostyrene is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. A Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.