Description

5-Fluoro-Quinoline-2-Carbaldehyde is a versatile and high-value fluorinated heterocyclic building block. This compound is essential for advanced organic synthesis, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Material Science: Serves as a building block for creating functionalized organic ligands, liquid crystals, and advanced polymers with specific electronic or optical properties.
• Chemical Synthesis: The aldehyde functional group makes it a crucial reactant for condensation reactions, such as the synthesis of Schiff bases, quinoline-fused heterocycles, and complex molecular architectures.
• Academic & Contract Research: Widely used in academic laboratories and CROs (Contract Research Organizations) for exploratory chemistry and hit-to-lead optimization programs.

Basic Information

Product Name	5-Fluoro-Quinoline-2-Carbaldehyde
CAS No.	1221280-85-8
Molecular Formula	C10H6FNO
Molecular Weight	175.16 g/mol
Synonyms	5-Fluoro-2-quinolinecarboxaldehyde; 5-Fluoroquinoline-2-carboxaldehyde; 2-Quinolinecarboxaldehyde, 5-fluoro-; 5-Fluoro-2-formylquinoline; 5-Fluoroquinoline-2-aldehyde
EINECS	Contact for details

Quality Control

Our 5-Fluoro-Quinoline-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and propensity to be easily oxidized, it is recommended to store the material under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.