Description

2,3-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Inden-1-One is a high-value, advanced pharmaceutical intermediate featuring a pinacol boronate ester functional group, which is critical for modern synthetic methodologies. This compound matters because it serves as a versatile building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures essential for drug discovery and development. It is primarily needed by research scientists and process chemists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Research: Used to create complex heterocyclic structures found in advanced pesticides and herbicides.
• Material Science: Serves as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and semiconductors.
• Chemical Synthesis: Employed in academic and industrial R&D for constructing indanone-based libraries and exploring new chemical spaces.
• Ligand & Catalyst Development: Utilized as a starting material for synthesizing specialized ligands and organometallic catalysts.

Basic Information

Product Name	2,3-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Inden-1-One
CAS No.	1221239-08-2
Molecular Formula	C15H19BO3
Molecular Weight	258.12 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-1H-inden-1-one; 1-Indanone, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-2,3-dihydro-; 4-(Pinacolatoboryl)-2,3-dihydro-1H-inden-1-one; 4-BPin Indan-1-one; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)indan-1-one
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Inden-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles for pharmaceutical intermediates, ensuring traceability and reliability for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.