Description

3-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is a high-purity, advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its core value lies in its boronic ester functional group, which is essential for modern cross-coupling reactions like the Suzuki-Miyaura reaction, enabling the efficient construction of complex molecules. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a crucial boronic ester coupling partner for forming carbon-carbon bonds between aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides.
• Material Science & OLED Development: Acts as a building block for creating organic light-emitting diode (OLED) materials and other advanced functional polymers.
• Ligand Synthesis for Catalysis: Employed in the preparation of sophisticated pyridine-based ligands used in homogeneous catalysis.
• Chemical Biology & Probe Development: Utilized in the creation of molecular probes and tags for studying biological systems.

Basic Information

Item	Details
Product Name	3-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine
CAS No.	1220696-49-0
Molecular Formula	C13H20BNO2
Molecular Weight	233.11 g/mol
Synonyms	3-Ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-ethylpyridine; 3-Ethylpyridine-5-boronic acid pinacol ester; 3-Ethyl-5-pyridinylboronic acid pinacol ester; 3-Ethyl-5-(pinacolboryl)pyridine; Pyridine, 3-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 1220696-49-0
EINECS	Contact for details

Quality Control

Our 3-Ethyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and when opening the container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.