Description

Methyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline-3-Carboxylate is a high-value, organoboron building block essential for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and precise construction of complex quinoline-based molecular architectures, which are pivotal in pharmaceutical and advanced materials research. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for drugs targeting various diseases where the quinoline scaffold is pharmacologically relevant.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron reagent for forming carbon-carbon bonds, enabling the modular construction of complex, functionalized quinoline derivatives.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate the quinoline moiety for enhanced efficacy.
• Material Science & OLED Development: Employed in the synthesis of organic semiconductors, light-emitting materials, and other advanced organic electronic components.
• Ligand and Catalyst Synthesis: Acts as a building block for creating novel chelating ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology & Probe Development: Utilized to create fluorescent probes or labeled compounds for biological imaging and target identification studies.

Basic Information

Product Name	Methyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline-3-Carboxylate
CAS No.	1220418-81-4
Molecular Formula	C20H24BNO4
Molecular Weight	353.22 g/mol
Synonyms	Methyl 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline-3-carboxylate; 6-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinoline-3-carboxylic acid methyl ester; 3-Quinolinecarboxylic acid, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester; Methyl 6-(pinacolatoboryl)quinoline-3-carboxylate; 6-Pinacolatoborylquinoline-3-carboxylic acid methyl ester; Quinoline-3-carboxylic acid, 6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 6-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Quinoline-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity, purity, and the absence of critical impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) and in a desiccator to prevent moisture absorption, which can affect stability and reactivity. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.