Description

6-Amino-2-Methylpyridin-3-Ylboronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical Suzuki-Miyaura cross-coupling building block, enabling the efficient construction of complex heterocyclic scaffolds. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates, particularly those containing functionalized pyridine cores.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and insecticides with targeted activity.
• Material Science Research: Used in the development of organic electronic materials, ligands, and metal-organic frameworks (MOFs).
• Suzuki-Miyaura Cross-Coupling Reactions: Enables carbon-carbon bond formation between the boronic ester and various aryl/heteroaryl halides under palladium catalysis.
• Library Synthesis for High-Throughput Screening: Facilitates the rapid generation of diverse compound libraries for biological activity testing.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways.

Basic Information

Product Name	6-Amino-2-Methylpyridin-3-Ylboronic Acid Pinacol Ester
CAS No.	1220219-97-5
Molecular Formula	C₁₃H₁₉BN₂O₂
Molecular Weight	246.11 g/mol
Synonyms	2-Methyl-6-aminopyridin-3-ylboronic acid pinacol ester; (6-Amino-2-methylpyridin-3-yl)boronic acid pinacol ester; 3-Borono-6-amino-2-methylpyridine pinacol ester; 6-Amino-2-methyl-3-pyridineboronic acid pinacol ester; 2-Methyl-6-amino-3-pyridinylboronic acid pinacol ester; 6-Amino-2-methyl-3-pyridylboronic acid pinacol ester; PINACOL (6-AMINO-2-METHYLPYRIDIN-3-YL)BORONATE
EINECS	Contact for details

Quality Control

Our 6-Amino-2-Methylpyridin-3-Ylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.