Description

3-Cyano-4-Methylphenylboronic Acid, Pinacol Ester is a high-purity, protected boronic acid derivative essential for advanced organic synthesis. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds in the synthesis of biaryl compounds, a common scaffold in pharmaceuticals and organic electronics.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly for constructing complex, functionalized aromatic systems.
• Agrochemical Synthesis: Serves as a building block for creating novel herbicides, fungicides, and insecticides with specific targeting properties.
• Materials Science Research: Employed in the development of organic light-emitting diodes (OLEDs), semiconductors, and liquid crystals due to its ability to introduce functional groups onto aromatic cores.
• Chemical Biology & Probe Development: Useful for synthesizing molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring specific, protected boronic acid functionality.

Basic Information

Product Name	3-Cyano-4-Methylphenylboronic Acid, Pinacol Ester
CAS No.	1220219-11-3
Molecular Formula	C14H18BNO2
Molecular Weight	243.11 g/mol
Synonyms	4-Methyl-3-cyanophenylboronic acid pinacol ester; (3-Cyano-4-methylphenyl)boronic acid pinacol ester; 2-(3-Cyano-4-methylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (3-cyano-4-methylphenyl)boronate; Boronic acid, B-(3-cyano-4-methylphenyl)-, 1,1-dimethylethyl ester; 3-CN-4-Me-PhBpin
EINECS	Contact for details

Quality Control

Our 3-Cyano-4-Methylphenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC-MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry standards for research and process chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.