Description

(3-Bromophenyl)(2,3-Difluorophenyl)Methanone is a high-purity diaryl ketone derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique halogenated aromatic structure, which provides a versatile scaffold for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and material science industries seeking to introduce specific bromine and fluorine substitutions.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders or requiring halogenated aromatic motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides, where the difluorophenyl and bromophenyl groups can contribute to binding affinity and environmental persistence.
• Ligand and Catalyst Development: Serves as a backbone for creating specialized ligands in transition metal catalysis or as a monomer for functional polymers in material science applications.
• Organic Electronic Materials: Investigated as a potential building block for electron-transport materials or photoactive layers in OLEDs and other electronic devices due to its conjugated ketone system.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological processes, leveraging the bromine atom for further functionalization via cross-coupling reactions.

Basic Information

Product Name	(3-Bromophenyl)(2,3-Difluorophenyl)Methanone
CAS No.	1220124-56-0
Molecular Formula	C13H7BrF2O
Molecular Weight	297.10 g/mol
Synonyms	3-Bromo-2',3'-difluorobenzophenone; 2,3-Difluoro-3'-bromobenzophenone; (3-Bromophenyl)(2,3-difluorophenyl)methanone; 1-(3-Bromophenyl)-2-(2,3-difluorophenyl)ethanone (common misnomer); Benzophenone, 3-bromo-2',3'-difluoro-; 1220124-56-0; (2,3-Difluorophenyl)(3-bromophenyl)methanone
EINECS	Contact for details

Quality Control

Our (3-Bromophenyl)(2,3-Difluorophenyl)Methanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.