Description

2-[1-(Tetrahydro-2-Furanylmethyl)-3-Pyrrolidinyl]-Acetic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and other therapeutic areas. It is essential for research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in process development and scale-up of new drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new drug molecules, especially those targeting neurological pathways.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the multi-step synthesis of complex APIs, leveraging its pyrrolidine-acetic acid scaffold.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing for clinical trial material supply.
• Bioconjugation & Prodrug Development: The carboxylic acid functional group allows for conjugation chemistry, useful in creating prodrugs or targeted delivery systems.

Basic Information

Product Name	2-[1-(Tetrahydro-2-Furanylmethyl)-3-Pyrrolidinyl]-Acetic Acid
CAS No.	1220036-12-3
Molecular Formula	C11H19NO3
Molecular Weight	213.27 g/mol
Synonyms	2-(1-((Tetrahydrofuran-2-yl)methyl)pyrrolidin-3-yl)acetic acid; 2-[1-(Oxolan-2-ylmethyl)pyrrolidin-3-yl]acetic acid; (3-Pyrrolidinyl)-Acetic Acid, 2-[1-(Tetrahydro-2-Furanylmethyl)-; THF-Pyrrolidine Acetic Acid Derivative; 1220036-12-3; Pyrrolidine-3-acetic acid, 1-((tetrahydro-2-furanyl)methyl)-
EINECS	Contact for details

Quality Control

Our 2-[1-(Tetrahydro-2-Furanylmethyl)-3-Pyrrolidinyl]-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area%)	≥ 99.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.