Description

1-(2-Piperidinylmethyl)Indoline Dihydrochloride is a high-purity, specialized organic salt used as a critical intermediate in advanced chemical synthesis. This compound is valued for its precise molecular structure, which enables the development of novel compounds with targeted biological or material properties. It is primarily required by research institutions and pharmaceutical companies engaged in medicinal chemistry, process development, and the synthesis of new chemical entities (NCEs).

Application

• Pharmaceutical Intermediate: Key building block in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic agents.
• Process Chemistry: Serves as a standard or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Chemical Reference Standard: Employed as an analytical standard for method development, validation, and quality control in R&D laboratories.
• Academic Research: Utilized in universities and research institutes for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	1-(2-Piperidinylmethyl)Indoline Dihydrochloride
CAS No.	1220021-57-7
Molecular Formula	C15H22N2 • 2HCl
Molecular Weight	311.27 g/mol (free base: 230.35 g/mol)
Synonyms	1-[(2-Piperidinyl)methyl]indoline dihydrochloride; Indoline, 1-[(2-piperidinyl)methyl]-, dihydrochloride; 1-(Piperidin-2-ylmethyl)indoline dihydrochloride; 2-(Indolin-1-ylmethyl)piperidine dihydrochloride
EINECS	Contact for details

Quality Control

Our 1-(2-Piperidinylmethyl)Indoline Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed and stored under dry conditions to prevent degradation. For long-term storage, consider using a desiccant.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.