Description

3-Pyridinecarboxylic Acid, 2-Chloro-5-(Trifluoromethyl)-, Ethyl Ester is a high-purity, multi-functional chemical intermediate designed for advanced synthesis. This compound is valued for its unique molecular architecture, which combines a halogenated pyridine core with a trifluoromethyl group and an ester functionality, making it a versatile building block for creating complex molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalytic processes and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and process chemistry optimization in laboratory-scale and pilot-scale production.

Basic Information

Product Name	3-Pyridinecarboxylic Acid, 2-Chloro-5-(Trifluoromethyl)-, Ethyl Ester
CAS No.	1188265-81-7
Molecular Formula	C9H7ClF3NO2
Molecular Weight	253.60 g/mol
Synonyms	Ethyl 2-Chloro-5-(trifluoromethyl)nicotinate; 2-Chloro-5-(trifluoromethyl)nicotinic Acid Ethyl Ester; Ethyl 2-Chloro-5-trifluoromethylpyridine-3-carboxylate; 2-Chloro-5-trifluoromethyl-pyridine-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-2-chloro-5-trifluoromethylpyridine; Nicotinic acid, 2-chloro-5-(trifluoromethyl)-, ethyl ester
EINECS	Contact for details

Quality Control

Our 3-Pyridinecarboxylic Acid, 2-Chloro-5-(Trifluoromethyl)-, Ethyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.