Description

(4-Methyl-1-Piperazinyl)(4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methanone Hcl is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of targeted therapeutic agents. It is primarily sought by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel drug candidates, especially within the central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Protease Inhibitor Development: The structural motif suggests potential application in the development of enzyme inhibitors.
• Kinase Inhibitor Synthesis: Serves as a core scaffold for the design and synthesis of potential kinase-targeted therapeutic agents.
• Chemical Biology Probes: Utilized in the creation of specialized molecular probes for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	(4-Methyl-1-Piperazinyl)(4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methanone Hydrochloride
CAS No.	1220017-91-3
Molecular Formula	C₁₂H₁₉N₅O • HCl
Molecular Weight	285.77 g/mol (Free base: 249.32 g/mol)
Synonyms	4-Methyl-1-piperazinyl(4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)methanone hydrochloride; 1-(4-Methylpiperazin-1-yl)-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carboxamide hydrochloride; 1220017-91-3; UNII-4K2VK8TQ6F; 4K2VK8TQ6F; Methanone, (4-methyl-1-piperazinyl)(4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridin-3-yl)-, hydrochloride (1:1)
EINECS	Contact for details

Quality Control

Our production of (4-Methyl-1-Piperazinyl)(4,5,6,7-Tetrahydro-1H-Pyrazolo[4,3-C]Pyridin-3-Yl)Methanone Hcl adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and related substances. Certificates of Analysis (COA) detailing all specifications are provided to ensure full traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.