Description

1-[4-(4-Piperidinyloxy)Phenyl]-1-Ethanonehydrochloride is a high-purity organic compound supplied as a hydrochloride salt. This advanced pharmaceutical intermediate is critical for the research and development of novel therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers requiring a reliable, high-quality building block for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates targeting various receptors.
• Chemical Research: Used in academic and industrial research for developing new chemical entities and studying structure-activity relationships (SAR).
• Preclinical Development: Serves as a critical material for producing batches of active pharmaceutical ingredients (APIs) for early-stage toxicology and pharmacology studies.
• Process Chemistry: Employed in route scouting and optimization for scalable API manufacturing processes.
• Reference Standard: Can be used as an analytical standard for method development and quality control in API production.

Basic Information

Product Name	1-[4-(4-Piperidinyloxy)Phenyl]-1-Ethanonehydrochloride
CAS No.	1219976-64-3
Molecular Formula	C14H19NO2·HCl
Molecular Weight	269.77 g/mol (Free base: 233.31 g/mol)
Synonyms	1-[4-(4-Piperidinyloxy)phenyl]ethanone hydrochloride; 4'-Piperidin-4-yloxyacetophenone hydrochloride; 1-(4-(Piperidin-4-yloxy)phenyl)ethan-1-one hydrochloride; 4-Acetylphenyl piperidin-4-yl ether hydrochloride; 1-[4-(4-Piperidyloxy)phenyl]ethanone HCl; 4-(4-Acetylphenoxy)piperidine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-[4-(4-Piperidinyloxy)Phenyl]-1-Ethanonehydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.