Description

1-(5-Fluoro-1H-Indol-2-Yl)Ethan-1-One is a high-purity fluorinated indole derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized indole core essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and agrochemicals. The CAS number for this compound is 1219930-11-6.

Application

This fluorinated indole derivative is a versatile intermediate with significant utility in several high-value research and development sectors.

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Research: Used in the development of new generation pesticides and herbicides, where the fluorine atom and indole scaffold can enhance biological activity and environmental stability.
• Material Science: Acts as a monomer or functional unit in the research of advanced organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Biochemical Probe Development: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and biological pathways.
• Academic & Contract Research: Essential for synthetic chemistry research in universities and contract research organizations (CROs) exploring new heterocyclic compounds and reaction methodologies.

Basic Information

Item	Detail
Product Name	1-(5-Fluoro-1H-Indol-2-Yl)Ethan-1-One
CAS No.	1219930-11-6
Molecular Formula	C10H8FNO
Molecular Weight	177.18 g/mol
Synonyms	2-Acetyl-5-fluoroindole; 5-Fluoro-2-acetylindole; 1-(5-Fluoro-1H-indol-2-yl)ethanone; 5-Fluoroindole-2-yl methyl ketone; Ethanone, 1-(5-fluoro-1H-indol-2-yl)-; 5-Fluoro-2-acetyl-1H-indole
EINECS	Contact for details

Quality Control

Our 1-(5-Fluoro-1H-Indol-2-Yl)Ethan-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment aligns with the standards expected for fine chemical and pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.