Description

2,3,4,4',5-Pentachlorobiphenyl-2',3',5',6'-D4 is a deuterated analog of a specific pentachlorinated biphenyl congener, serving as a critical internal standard and reference material for high-precision analytical chemistry. This compound is essential for ensuring accurate quantification and method validation in complex environmental and biological matrices, where trace-level detection is paramount. It is primarily needed by analytical laboratories, environmental testing facilities, and research institutions focused on persistent organic pollutant (POP) analysis, PCB fate and transport studies, and regulatory compliance testing.

Application

• Internal Standard for Mass Spectrometry: Used as a deuterated internal standard in GC-MS and LC-MS/MS analysis for the accurate quantification of native PCB congeners in environmental and food samples.
• Method Development & Validation: Critical for developing, calibrating, and validating analytical methods according to EPA, EU, and other international standards for PCB detection.
• Environmental Monitoring: Employed in the analysis of soil, sediment, water, and air samples to study PCB contamination, bioaccumulation, and remediation efforts.
• Toxicological & Metabolic Studies: Used in research to investigate the metabolic pathways, pharmacokinetics, and toxicological profiles of specific PCB congeners.
• Quality Control/Quality Assurance (QC/QA): Serves as a key component in laboratory QC/QA protocols to ensure data accuracy, precision, and recovery rates in routine testing.
• Certified Reference Material (CRM) Production: Acts as a primary material for the preparation of certified reference materials and proficiency testing samples.

Basic Information

Product Name	2,3,4,4',5-Pentachlorobiphenyl-2',3',5',6'-D4
CAS No.	1219799-24-2
Molecular Formula	C12H2D4Cl5
Molecular Weight	334.43 g/mol (for D4 isotopologue)
Synonyms	PCB 118-D4; 2,3,4,4',5-Pentachlorobiphenyl-d4; 2,3,4,4',5-Pentachloro[2',3',5',6'-2H4]biphenyl; IUPAC: 1,2,3,4-Tetrachloro-5-(2,3,5,6-tetradeuterio-4-chlorophenyl)benzene; Deuterated PCB 118; [2H4]-PCB 118; 2,3,4,4',5-PentaCB-d4
EINECS	Contact for details

Quality Control

Every batch of our deuterated PCB standards is produced and analyzed under strict quality management systems to ensure the highest levels of isotopic purity and chemical authenticity. Comprehensive characterization is performed using NMR, HRMS, and HPLC to confirm structure, isotopic enrichment, and chemical purity. A detailed Certificate of Analysis (COA) is provided with each product, containing batch-specific data on purity, concentration, and analytical results. Our quality commitment supports compliance with ISO/IEC 17025 and GLP principles for analytical laboratories.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dedicated freezer. For long-term storage under an inert atmosphere (argon or nitrogen), contact us for specific recommendations. Allow the sealed vial to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid or solution (as specified)
Identification (NMR)	Conforms to structure
Isotopic Purity (D-content)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98%
Concentration (if in solution)	50 µg/mL ± 5% in nonane or iso-octane
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.