Description

n-Nitroso-Di-n-Butylamine-D18 is a stable isotope-labeled analog of a nitrosamine compound, specifically deuterated at 18 positions. This high-purity standard is critical for ensuring analytical accuracy and traceability in sensitive detection methods. It is primarily required by analytical laboratories and research institutions in the pharmaceutical, environmental, and food safety sectors for use as an internal standard in mass spectrometry.

Application

• Used as an internal standard for the precise quantification of N-nitrosodi-n-butylamine (NDBA) and related nitrosamines via LC-MS/MS and GC-MS.
• Essential in pharmaceutical quality control for monitoring nitrosamine impurities in active pharmaceutical ingredients (APIs) and finished drug products to comply with regulatory guidelines (e.g., FDA, EMA).
• Applied in environmental analysis for tracing nitrosamine contaminants in water, soil, and industrial waste.
• Utilized in food and beverage safety testing to detect nitrosamine levels in processed foods.
• Supports toxicological and metabolic studies in academic and industrial research, enabling the study of nitrosamine behavior and pathways.
• Facilitates method development and validation in analytical chemistry laboratories to ensure robustness and regulatory compliance.

Basic Information

Item	Details
Product Name	n-Nitroso-Di-n-Butylamine-D18
CAS No.	1219798-82-9
Molecular Formula	C8D18N2O
Molecular Weight	174.33 g/mol (theoretical)
Synonyms	NDBA-d18; N-Nitrosodi-n-butylamine-d18; N-Nitroso-N-butyl-1-butylamine-d18; Deuterated N-Nitrosodi-n-butylamine; N-Nitrosodibutylamine-d18; N,N-Dibutylnitrous amide-d18; Di-n-butylnitrosamine-d18; DBNA-d18
EINECS	Contact for details

Quality Control

Our n-Nitroso-Di-n-Butylamine-D18 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for analytical reference standards. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical results is provided with every shipment to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C (refrigerated) or as specified on the label or COA. Due to its light-sensitive and highly volatile nature, prolonged exposure to ambient conditions should be avoided. Keep container tightly sealed in a cool, dry, and well-ventilated place.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0% (chemical purity)
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.