Description

Temephos-D12 (O,O,O',O'-Tetramethyl-D12) is a stable isotope-labeled analog of the organophosphate insecticide Temephos, specifically deuterated at all methyl positions. This compound is an essential internal standard for high-precision analytical methods, enabling accurate quantification and minimizing matrix effects in complex samples. It is primarily required by analytical laboratories and environmental testing facilities engaged in method development, residue analysis, and regulatory compliance monitoring.

Application

• Internal Standard for Mass Spectrometry (GC-MS/LC-MS): Used as a quantitative reference in the analysis of Temephos residues in environmental and biological matrices.
• Environmental Fate and Metabolism Studies: Enables precise tracking and quantification of Temephos and its degradation products in soil and water studies.
• Food Safety and Residue Analysis: Critical for ensuring accurate results in the testing of agricultural products for pesticide residues to meet global food safety standards.
• Pharmaceutical Impurity Profiling: Supports analytical methods for detecting and quantifying potential genotoxic impurities in pharmaceutical synthesis.
• Quality Control and Method Validation: Serves as a certified reference material for calibrating equipment and validating analytical methods in ISO 17025 accredited labs.
• Dioxin and POPs Analysis Support: Employed in sophisticated multi-residue methods for persistent organic pollutants where isotope dilution is the gold standard.

Basic Information

Product Name	Temephos-D12 (O,O,O',O'-Tetramethyl-D12)
CAS No.	1219795-39-7
Molecular Formula	C16H2D12O6P2S2
Molecular Weight	472.48 g/mol
Synonyms	Abate-D12; Temephos-d12; O,O,O',O'-Tetramethyl-d12 O,O'-(thiodi-4,1-phenylene) bis(phosphorothioate); Deuterated Temephos; Phosphorothioic acid, O,O'-(thiodi-4,1-phenylene) O,O,O',O'-tetrakis(methyl-d3) ester; 4,4'-O,O,O',O'-Tetramethyl-d12 thiodiphenyl bis(phosphorothioate); (4-((Methoxy-d3)phosphinothioyloxy)phenyl) sulfanylphenyl (methoxy-d3)phosphonothioate
EINECS	Contact for details

Quality Control

Every batch of Temephos-D12 is produced and analyzed under strict quality protocols to ensure the highest isotopic purity and chemical stability. Our quality system is designed to meet the rigorous demands of analytical reference standard applications. Comprehensive Certificates of Analysis (COA) are provided, detailing parameters such as isotopic enrichment, chemical purity, and solvent content. We support compliance with ISO, GLP, and REACH frameworks, and specifications can be aligned with your method validation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to maintain isotopic integrity and prevent contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (MS)	≥ 98.0 atom % D
Chemical Purity (Titration)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.