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2-(4-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane CAS NO 1219741-94-2
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CAS No.:1219741-94-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
2-(4-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective carbon-carbon bond formation, particularly in the synthesis of complex pharmaceutical intermediates and advanced materials. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality reagents for Suzuki-Miyaura cross-coupling reactions.
Application
- Pharmaceutical Intermediate Synthesis: A key reagent for constructing biaryl and heterobiaryl motifs prevalent in active pharmaceutical ingredients (APIs).
- Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
- Material Science & OLED Research: Serves as a precursor for creating organic light-emitting diode (OLED) materials and other functional organic electronic compounds.
- Ligand & Catalyst Preparation: Employed in the development of novel ligands and organometallic catalysts for asymmetric synthesis.
- Chemical Biology & Probe Development: Utilized for labeling and modifying biomolecules in drug discovery and diagnostic research.
- Polymer Chemistry: Acts as a monomer or functionalization agent in the synthesis of specialty polymers with tailored properties.
Basic Information
| Product Name | 2-(4-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane |
| CAS No. | 1219741-94-2 |
| Molecular Formula | C15H21BO2 |
| Molecular Weight | 244.14 g/mol |
| Synonyms | 4-Cyclopropylphenylboronic acid pinacol ester; (4-Cyclopropylphenyl)boronic acid pinacol ester; 2-(4-Cyclopropylphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-Cyclopropylbenzeneboronic acid pinacol ester; 1-Cyclopropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzene; Cyclopropylphenylboronic acid pinacol ester; Pinacol (4-cyclopropylphenyl)boronate |
| EINECS | Contact for details |
Quality Control
Our 2-(4-Cyclopropylphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including NMR (1H, 13C, 11B), HPLC, and GC analysis, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Assay (HPLC) | ≥97.0% |
| Water Content (KF) | ≤0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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