Description

5-Methoxy-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is a high-value, functionalized indole derivative containing a pinacol boronate ester group, making it a crucial building block for modern synthetic chemistry. This compound is specifically engineered for use in Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex carbon-carbon bonds. It is an essential intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular construction.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in creating complex heterocyclic scaffolds for oncology, CNS, and anti-inflammatory therapies.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products, leveraging the indole core's bioactivity.
• Material Science: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials, where the indole-boronate structure enables fine-tuning of electronic properties.
• Chemical Research & Development: An indispensable reagent in academic and industrial R&D labs for methodology development and the synthesis of complex organic molecules via palladium-catalyzed cross-coupling.
• Ligand and Catalyst Development: Can be utilized to synthesize novel bidentate or polydentate ligands for catalysis.
• Library Synthesis for Drug Discovery: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in early-stage drug discovery.

Basic Information

Product Name	5-Methoxy-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole
CAS No.	1219637-79-2
Molecular Formula	C15H20BNO3
Molecular Weight	273.14 g/mol
Synonyms	7-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-5-methoxy-1H-indole; 5-Methoxy-7-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)indole; 5-Methoxy-1H-indole-7-boronic acid pinacol ester; 7-Borono-5-methoxyindole pinacol ester; 5-Methoxy-7-boronoindole pinacol ester; 5-Methoxyindole-7-boronic acid pinacol ester; CAS 1219637-79-2
EINECS	Contact for details

Quality Control

Our 5-Methoxy-7-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1H-Indole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR (1H and 13C), and mass spectrometry to confirm identity and purity. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its moisture-sensitive nature. Allow the sealed container to reach room temperature before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.