Description

1-(4-Fluorobenzoyl)-4-Oxo-2-Pyrrolidinecarboxylic Acid is a high-purity, fluorinated pyrrolidine derivative, serving as a critical advanced pharmaceutical intermediate (API intermediate) and a versatile building block in organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with potential biological activity, particularly in medicinal chemistry. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting neurological and metabolic disorders.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new pharmacophores.
• Protease Inhibitor Synthesis: Serves as a core structure or precursor in the development of protease enzyme inhibitors.
• Agrochemical Development: Employed in the research and synthesis of new-generation pesticides and herbicides.
• Fine Chemical Synthesis: Acts as a versatile reagent for constructing complex, fluorinated heterocyclic compounds in custom synthesis projects.
• Bioconjugation & Labeling: The carboxylic acid functionality allows for conjugation to biomolecules for research and diagnostic applications.

Basic Information

Product Name	1-(4-Fluorobenzoyl)-4-Oxo-2-Pyrrolidinecarboxylic Acid
CAS No.	1219426-25-1
Molecular Formula	C12H10FNO4
Molecular Weight	251.21 g/mol
Synonyms	4-Oxo-1-(4-fluorobenzoyl)-2-pyrrolidinecarboxylic acid; 1-(4-Fluorobenzoyl)-4-oxopyrrolidine-2-carboxylic acid; 4-Fluorobenzoyl-4-oxoproline; (4-Fluorobenzoyl)-DHP; 2-Pyrrolidinecarboxylic acid, 1-(4-fluorobenzoyl)-4-oxo-; Fluorinated pyrrolidone carboxylic acid derivative; API Intermediate 1219426-25-1
EINECS	Contact for details

Quality Control

Our 1-(4-Fluorobenzoyl)-4-Oxo-2-Pyrrolidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.