Description

2-Pyridinone-8-Boronic Ester is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in enabling efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery, catalyst development, and material science applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds containing complex heterocyclic structures.
• Agrochemical Synthesis: Used in the research and production of novel pesticides, herbicides, and fungicides that require specific pyridine-based scaffolds.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing partner for forming carbon-carbon bonds under mild conditions, a cornerstone of modern medicinal chemistry.
• Material Science Research: Employed in the development of organic electronic materials, ligands for catalysts, and novel polymers.
• Chemical Biology & Proteomics: Utilized in the design and synthesis of molecular probes and inhibitors for studying biological pathways.
• Academic & R&D Laboratories: A valuable reagent for methodological development and the synthesis of novel chemical entities in research settings.

Basic Information

Product Name	2-Pyridinone-8-Boronic Ester
CAS No.	1219130-55-8
Molecular Formula	C11H14BNO3
Molecular Weight	219.05 g/mol
Synonyms	8-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one; 2-Oxo-1,2-dihydroquinoline-8-boronic acid pinacol ester; Quinolin-2(1H)-one, 8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-; 8-(Tetramethyl-1,3,2-dioxaborolan-2-yl)quinolin-2(1H)-one; 2-Hydroxyquinoline-8-boronic acid pinacol ester; 8-Boronic ester of 2-pyridinone
EINECS	Contact for details

Quality Control

Our 2-Pyridinone-8-Boronic Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards required for cGMP and ISO-certified manufacturing environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.