Description

2-Pyridone-5-Boronic Ester is a high-value boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a key intermediate in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for constructing complex molecular architectures via palladium-catalyzed cross-coupling.
• Ligand Synthesis: Can be utilized in the preparation of novel ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	2-Pyridone-5-Boronic Ester
CAS No.	1219130-53-6
Molecular Formula	C7H8BNO2 (Base structure; specific ester varies)
Molecular Weight	Contact for details
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-2(1H)-one
2-Hydroxy-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
5-(Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyridin-2-one
2-Pyridone-5-boronic acid pinacol ester
5-Borono-2-pyridone pinacol ester
5-(2-Pyridone)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-Pyridone-5-Boronic Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.