Description

(Z)-3-(3-Chloro-2-Fluorophenyl)-2-(4-Chloro-2-Fluorophenyl)-2-Propenenitrile is a high-value, multi-halogenated organic intermediate with a defined stereochemistry. This compound matters for its role as a critical building block in the synthesis of advanced, functional molecules, offering precise structural control. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders or inflammatory diseases.
• Agrochemical Research: Serves as a building block for developing new generation pesticides and herbicides with improved efficacy and selectivity.
• Material Science: Used in the research and development of specialty polymers and liquid crystal materials, leveraging its rigid, halogenated structure.
• Organic Synthesis: A versatile reagent for constructing complex molecular architectures via cross-coupling reactions, cyclizations, or as a dienophile in Diels-Alder reactions.
• Chemical Biology: Employed as a probe or tag in biochemical research due to its unique chemical handle (nitrile group) and fluorinated aromatic rings.

Basic Information

Product Name	(Z)-3-(3-Chloro-2-Fluorophenyl)-2-(4-Chloro-2-Fluorophenyl)-2-Propenenitrile
CAS No.	1219086-87-9
Molecular Formula	C15H7Cl2F2N
Molecular Weight	310.13 g/mol
Synonyms	(Z)-3-(3-Chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)acrylonitrile; (Z)-2,3-Bis(3-chloro-2-fluorophenyl)acrylonitrile (isomeric); 2-Propenenitrile, 3-(3-chloro-2-fluorophenyl)-2-(4-chloro-2-fluorophenyl)-, (Z)-; Z-Isomer of Dichlorodifluorostilbene Nitrile; Acrylonitrile derivative CAS 1219086-87-9
EINECS	Contact for details

Quality Control

Our production of (Z)-3-(3-Chloro-2-Fluorophenyl)-2-(4-Chloro-2-Fluorophenyl)-2-Propenenitrile adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. All materials are characterized by advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, isomeric content, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep container tightly sealed when not in use to prevent moisture absorption or contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Isomeric Purity (Z-Isomer)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.