Description

1H-Imidazol-2-Ylboronic Acid Hydrochloride is a high-value organoboron building block, specifically a boronic acid derivative of imidazole, essential for modern synthetic chemistry. Its primary value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecules. This compound is critically needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing imidazole-containing drug candidates, including kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of novel fungicides and herbicides that incorporate the imidazole heterocycle.
• Material Science Research: Employed in the creation of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of activity-based probes.
• Catalyst Ligand Precursor: Used to synthesize N-heterocyclic carbene (NHC) ligands and other organometallic catalysts.
• Academic & Contract Research: Fundamental reagent for methodological development in cross-coupling and heterocyclic chemistry.

Basic Information

Product Name	1H-Imidazol-2-Ylboronic Acid Hydrochloride
CAS No.	1219080-61-1
Molecular Formula	C3H6BClN2O2
Molecular Weight	148.36 g/mol
Synonyms	2-Imidazoleboronic Acid Hydrochloride; (1H-Imidazol-2-yl)boronic Acid Hydrochloride; 2-Borono-1H-imidazole Hydrochloride; Imidazole-2-boronic Acid HCl; 1H-Imidazole-2-boronic Acid Hydrochloride Salt; 2-Imidazolylboronic Acid HCl
EINECS	Contact for details

Quality Control

Our 1H-Imidazol-2-Ylboronic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term stability and to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Assay	≥ 97%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.