Description

Isoquinolin-3-Ylboronic Acid CAS NO 1219080-59-7 is a high-purity boronic acid derivative, a crucial building block in modern synthetic organic chemistry. Its primary value lies in its role as a versatile coupling partner in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who are developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing isoquinoline-based drug candidates in medicinal chemistry programs, targeting a wide range of therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the isoquinoline moiety can impart specific biological activity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Catalyst & Ligand Development: Employed in the synthesis of novel chiral or functionalized ligands for asymmetric catalysis and transition metal complexes.
• Chemical Biology Probes: Utilized to create tagged molecules or inhibitors for studying biological pathways and protein functions.
• Academic & Contract Research: A fundamental reagent for methodology development and complex molecule synthesis in university and CRO laboratories.

Basic Information

Product Name	Isoquinolin-3-Ylboronic Acid
CAS No.	1219080-59-7
Molecular Formula	C9H8BNO2
Molecular Weight	172.98 g/mol
Synonyms	3-Isoquinolineboronic Acid; (Isoquinolin-3-yl)boronic Acid; 3-Boronoisoquinoline; Isoquinoline-3-boronic Acid; B-(3-Isoquinolinyl)boronic Acid; 1219080-59-7; 3-Isoquinolylboronic Acid
EINECS	Contact for details

Quality Control

Every batch of Isoquinolin-3-Ylboronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and mass spectrometry, to ensure high chemical purity and consistent performance in sensitive coupling reactions. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥95% (Typical 97-99%)
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.