Description

Bicyclo[2.2.1]Hept-2-En-2-Ylboronic Acid Pinacol Ester is a specialized organoboron reagent, specifically a norbornene-derived boronic ester, widely used in advanced organic synthesis. Its core value lies in enabling efficient and selective carbon-carbon bond formation, particularly in Suzuki-Miyaura cross-coupling reactions, which are fundamental to constructing complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery, catalyst development, and polymer synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those with complex, strained ring systems.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its unique structure for bioactivity.
• Material Science & Polymer Chemistry: Serves as a monomer or functionalization agent in the creation of specialty polymers, resins, and advanced materials with tailored properties.
• Catalyst & Ligand Development: Employed in the preparation of novel metal-organic frameworks (MOFs) and chiral ligands for asymmetric catalysis.
• Academic & Industrial R&D: A critical reagent for methodological development in organic chemistry, enabling new synthetic pathways and transformations.
• Fine Chemical Production: Integral to the multi-step synthesis of complex fine chemicals and specialty flavors/fragrances.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-2-En-2-Ylboronic Acid Pinacol Ester
CAS No.	1219021-46-1
Molecular Formula	C₁₃H₂₁BO₂
Molecular Weight	220.11 g/mol
Synonyms	5-Norbornene-2-boronic acid pinacol ester; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)bicyclo[2.2.1]hept-2-ene; Norborn-2-ene-2-boronic acid pinacol ester; Bicyclo[2.2.1]hept-2-ene-2-boronic acid pinacol ester; 5-Norbornene-2-ylboronic acid pinacol ester; 2-Bicyclo[2.2.1]hept-2-en-2-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-2-En-2-Ylboronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Production adheres to cGMP principles where applicable, and all materials are fully characterized by spectroscopic and chromatographic methods. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.