Description

2-Diethylaminopyrimidine-5-Boronic Acid, Pinacol Ester is a high-value, organoboron building block specifically designed for advanced synthetic chemistry. This compound matters for its role as a key intermediate in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily needed by researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used to create advanced pyrimidine-based herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Materials Science Research: Serves as a building block for constructing organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs producing specialized fine chemicals for client projects.

Basic Information

Product Name	2-Diethylaminopyrimidine-5-Boronic Acid, Pinacol Ester
CAS No.	1218791-45-7
Molecular Formula	C14H24BN3O2
Molecular Weight	277.17 g/mol
Synonyms	5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-diethylpyrimidin-2-amine; 2-(Diethylamino)-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine; 2-Diethylamino-5-(pinacolboronato)pyrimidine; 2-DEA-5-Bpin Pyrimidine; B-2-(Diethylamino)pyrimidin-5-yl-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; (2-(Diethylamino)pyrimidin-5-yl)boronic acid pinacol ester; 1218791-45-7
EINECS	Contact for details

Quality Control

Every batch of 2-Diethylaminopyrimidine-5-Boronic Acid, Pinacol Ester undergoes rigorous analytical testing to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Our quality protocols are designed to meet the stringent requirements of advanced synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (NMR)	Conforms
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.