Description

2-(N,N,n-Trimethylammonium)Phenylboronic Acid, Pinacol Ester, Iodide Salt is a specialized quaternary ammonium-functionalized boronic ester, a key building block in modern organic synthesis and materials science. Its unique structure combines a protected boronic acid moiety with a permanent cationic charge, making it invaluable for applications requiring water solubility, controlled reactivity, or specific ionic interactions. This high-purity intermediate is primarily sought by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced polymer industries for developing novel active ingredients and functional materials.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Acts as a water-soluble, charged boronic ester reagent for coupling with aryl halides in aqueous or mixed solvent systems.
• Pharmaceutical Intermediate: Serves as a key synthon in the development of drug candidates, particularly those requiring cationic or zwitterionic properties for enhanced bioavailability.
• Polymer & Material Science: Used in the synthesis of functionalized polymers, ionic liquids, and stimuli-responsive materials where the permanent charge and boronate group enable unique properties.
• Bioconjugation & Sensor Development: Facilitates the labeling and modification of biomolecules (e.g., sugars, glycoproteins) via boronate ester chemistry under physiologically relevant conditions.
• Agrochemical Synthesis: Employed in creating novel active ingredients with improved solubility and systemic activity in plants.
• Catalyst & Ligand Design: Provides a versatile scaffold for constructing charged ligands for transition metal catalysis.

Basic Information

Product Name	2-(N,N,n-Trimethylammonium)Phenylboronic Acid, Pinacol Ester, Iodide Salt
CAS No.	1218791-40-2
Molecular Formula	C16H27BINO2
Molecular Weight	427.11 g/mol
Synonyms	(2-(Trimethylammonio)phenyl)boronic acid pinacol ester iodide; 2-Trimethylammoniophenylboronic acid pinacol ester iodide; N,N,N-Trimethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenaminium iodide; 2-(N,N,N-Trimethylammonium)benzeneboronic acid pinacol ester iodide; Quaternary Ammonium Boronic Ester Salt; B-(2-(Trimethylammonio)phenyl)boronic acid pinacol ester iodide; Water-soluble phenylboronic ester salt
EINECS	Contact for details

Quality Control

Our production of 2-(N,N,n-Trimethylammonium)Phenylboronic Acid, Pinacol Ester, Iodide Salt adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical characterization, including NMR (1H, 13C, 11B), HPLC for purity assessment, and mass spectrometry for identity confirmation. We provide detailed Certificates of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or manufacturing specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed in a desiccated environment to maintain stability and purity. Handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.