Description

Methyl 3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate is a high-value, functionalized picolinate derivative containing a pinacol boronate ester group. This compound serves as a critical synthetic intermediate, enabling efficient cross-coupling reactions for the construction of complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in Suzuki-Miyaura cross-couplings for synthesizing drug candidates, especially those containing biphenyl or heterobiaryl motifs.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Precursor for creating organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed in the synthesis of probes and tool compounds for studying biological pathways and protein function.
• Academic & Contract Research: Essential reagent for methodological development in organic synthesis and catalysis research.
• Custom Synthesis: Serves as a starting material for the contract manufacturing of specialty fine chemicals and advanced intermediates.

Basic Information

Product Name	Methyl 3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate
CAS No.	1218791-31-1
Molecular Formula	C15H22BNO4
Molecular Weight	291.15 g/mol
Synonyms	Methyl 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinate; 3-Methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)picolinic acid methyl ester; Methyl 5-Borono-3-methylpicolinate Pinacol Ester; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-3-methylpicolinic Acid Methyl Ester; 2-Pyridinecarboxylic acid, 3-methyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Methyl-5-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Picolinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.