Description

N,n-Dimethyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a specialized aromatic amine derivative containing a nitro group and a pinacol boronate ester, making it a valuable advanced pharmaceutical intermediate and key building block in organic synthesis. Its molecular architecture is designed for efficient cross-coupling reactions, particularly Suzuki-Miyaura couplings, which are fundamental for constructing complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require high-purity, functionalized intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex biaryl or heterobiaryl structures.
• Suzuki-Miyaura Cross-Coupling Reactions: The pinacol boronate ester functional group makes it an ideal reagent for palladium-catalyzed coupling with aryl halides, enabling efficient carbon-carbon bond formation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic amine backbones.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology & Proteomics: Can be utilized as a building block for synthesizing molecular probes and tags due to its reactive amine and boronate groups.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	N,n-Dimethyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1218791-24-2
Molecular Formula	C14H21BN2O4
Molecular Weight	292.14 g/mol
Synonyms	2-Nitro-N,N-dimethyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethyl-2-nitroaniline; 2-Nitro-4-(pinacolatoboryl)-N,N-dimethylaniline; N,N-Dimethyl-2-nitro-4-(pinacolatoboryl)aniline; 1218791-24-2; 4-Borono-2-nitro-N,N-dimethylaniline pinacol ester; 2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N,N-dimethylbenzenamine
EINECS	Contact for details

Quality Control

Our production of N,n-Dimethyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline adheres to stringent quality management systems to ensure batch-to-batch consistency and high purity. Every lot undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to verify identity, potency, and impurity profiles. Certificates of Analysis (COA) detailing all specifications and test results are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥96.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.