Description

n-Butyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a high-value, advanced pharmaceutical intermediate and organic building block featuring a pinacol boronate ester functional group. This compound is critical for enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental to modern medicinal chemistry and materials science. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring aryl-aryl bond formation.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that incorporate complex aromatic structures.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport materials and emissive layer components in display and lighting technologies.
• Polymer Chemistry: Employed to create functionalized monomers for specialty polymers with tailored electronic or optical properties.
• Material Science Research: Facilitates the development of organic semiconductors, conductive polymers, and other advanced functional materials.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.

Basic Information

Product Name	n-Butyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1218791-22-0
Molecular Formula	C16H25BN2O4
Molecular Weight	320.19 g/mol
Synonyms	2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-butyl-aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-nitro-N-butylbenzenamine; N-Butyl-2-nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline; 1218791-22-0; Boronic acid, B-[4-[(butylamino)-3-nitrophenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-N-butyl-2-nitroaniline
EINECS	Contact for details

Quality Control

Our production of n-Butyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder or solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.