Description

n-Isopropyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is a specialized boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl and heterobiaryl structures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for drug discovery, catalyst development, and functional material synthesis.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex aromatic and heteroaromatic systems.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific biaryl motifs.
• Material Science Research: Building block for creating organic electronic materials, such as those used in OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Serves as a starting material for synthesizing novel ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological processes.
• Polymer Chemistry: Monomer or cross-linking agent for the synthesis of specialty polymers with tailored properties.

Basic Information

Product Name	n-Isopropyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline
CAS No.	1218791-21-9
Molecular Formula	C15H23BN2O4
Molecular Weight	306.17 g/mol
Synonyms	2-Nitro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-N-(propan-2-yl)aniline; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-nitro-N-isopropylaniline; 2-Nitro-4-(pinacolatoboryl)-N-isopropylaniline; N-Isopropyl-2-nitro-4-(pinacolatoboryl)aniline; 1218791-21-9; Boronic acid, B-[2-nitro-4-[(1-methylethyl)amino]phenyl]-, pinacol ester; B-[2-Nitro-4-(isopropylamino)phenyl]boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our n-Isopropyl-2-Nitro-4-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)Aniline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent lot-to-lot performance suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to handle and store the material under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation, especially after opening the original container. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.