Description

2-(Ethylaminomethyl)Phenylboronic Acid, Pinacol Ester is a specialized organoboron compound that serves as a protected boronic acid derivative, offering enhanced stability for handling and storage. This compound is a crucial building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex biaryl and heterobiaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of new active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon for constructing drug candidates, especially those containing biphenyl or aryl-heteroaryl motifs via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) where precise molecular architecture is critical.
• Chemical Biology & Probe Development: Acts as a versatile handle for bioconjugation and the creation of molecular probes for diagnostic and imaging applications.
• Process Chemistry & Scale-up: Suitable for optimizing and scaling synthetic routes from laboratory to pilot plant, thanks to the pinacol ester's improved handling properties.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and for custom synthesis projects.

Basic Information

Product Name	2-(Ethylaminomethyl)Phenylboronic Acid, Pinacol Ester
CAS No.	1218791-16-2
Molecular Formula	C15H24BNO2
Molecular Weight	261.17 g/mol
Synonyms	2-[(Ethylamino)methyl]benzeneboronic acid pinacol ester; N-Ethyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzylamine; 2-(Ethylaminomethyl)phenylboronic acid pinacol ester; (2-((Ethylamino)methyl)phenyl)boronic acid pinacol ester; B-[2-[(Ethylamino)methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1218791-16-2; Ethyl-[2-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)-benzyl]-amine
EINECS	Contact for details

Quality Control

Our 2-(Ethylaminomethyl)Phenylboronic Acid, Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment supports applications in GMP and ISO-compliant environments, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and may require storage under an inert atmosphere for long-term preservation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.