Description

1-(Toluene-4-Sulfonyl)-1H-Pyrrole-3-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid ester building block designed for advanced organic synthesis. This compound is critical for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex molecular architectures. It is an essential reagent for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require reliable, high-quality intermediates for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for creating novel biaryl and heterobiaryl structures prevalent in modern drug candidates.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific aryl-aryl bond formations.
• Material Science Research: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where precise molecular conjugation is needed.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for studying biological systems.
• Academic & Industrial R&D: A fundamental reagent in laboratories focused on methodology development and the synthesis of complex natural products or novel chemical entities.

Basic Information

Product Name	1-(Toluene-4-Sulfonyl)-1H-Pyrrole-3-Boronic Acid Pinacol Ester
CAS No.	1218791-03-7
Molecular Formula	C₁₇H₂₂BNO₄S
Molecular Weight	347.24 g/mol
Synonyms	1H-Pyrrole-3-boronic acid, 1-[(4-methylphenyl)sulfonyl]-, 1,1-dimethylethyl ester; 1-Tosyl-1H-pyrrole-3-boronic acid pinacol ester; 3-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrole; 1-(p-Toluenesulfonyl)-1H-pyrrole-3-boronic acid pinacol ester; 1-(4-Methylbenzenesulfonyl)-1H-pyrrole-3-boronic acid pinacol ester; 3-Borono-1-tosylpyrrole pinacol ester; N-Tosyl-3-pyrrolylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-(Toluene-4-Sulfonyl)-1H-Pyrrole-3-Boronic Acid Pinacol Ester is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for sensitive coupling reactions. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable and support compliance with REACH and other global regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.