Description

6-Bromoindole-2-Boronic Acid Pinacol Ester is a high-value, organoboron building block crucial for modern synthetic chemistry, particularly in cross-coupling reactions. Its core value lies in enabling the efficient and selective construction of complex indole-based molecular architectures, which are prevalent in active pharmaceutical ingredients (APIs) and advanced materials. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-purity intermediates for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel indole derivatives with potential biological activity.
• Agrochemical Research: Used in the discovery and development of new crop protection agents and herbicides that incorporate functionalized indole scaffolds.
• Material Science: Serves as a building block for creating organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, where the indole unit is integral.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and labeled compounds for studying biological pathways and protein interactions.
• Academic & Contract Research: A vital reagent for methodology development in academic laboratories and for custom synthesis projects in contract research organizations (CROs).

Basic Information

Product Name	6-Bromoindole-2-Boronic Acid Pinacol Ester
CAS No.	1218791-00-4
Molecular Formula	C₁₄H₁₇BBrNO₂
Molecular Weight	322.01 g/mol
Synonyms	6-Bromo-1H-indole-2-boronic acid pinacol ester; 2-(6-Bromo-1H-indol-2-yl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 6-Bromoindole-2-boronic acid, pinacol ester; 6-Bromo-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-indole; 6-Bromo-1H-indole-2-boronic acid, cyclic ester with pinacol; B-(6-Bromo-1H-indol-2-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 6-Bromoindole-2-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our commitment to quality assurance supports your research and development needs with reliable, consistent material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.