Description

Piperidine-4-Boronic Acid Pinacol Ester Hcl is a high-value, protected boronic acid derivative crucial for modern synthetic chemistry. This compound serves as a key building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical synthesis, and advanced material science.

Application

• Pharmaceutical Intermediate: A critical precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced crop protection agents and herbicides through palladium-catalyzed coupling.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and functional polymers.
• Chemical Biology & Proteomics: Acts as a versatile handle for bioconjugation and the synthesis of molecular probes and inhibitors.
• Academic & Contract Research: Essential for methodology development and exploratory synthesis in academic and industrial research laboratories.

Basic Information

Product Name	Piperidine-4-Boronic Acid Pinacol Ester Hcl
CAS No.	1218790-99-8
Molecular Formula	C11H23BClNO2
Molecular Weight	247.57 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine hydrochloride; 1-Boc-4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine HCl (common precursor); 4-Piperidineboronic acid pinacol ester hydrochloride; tert-Butyl 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)piperidine-1-carboxylate hydrochloride; 4-(Pinacolatoboryl)piperidine HCl; N-Boc-4-(pinacolboron)piperidine hydrochloride; 4-Borono-1-Boc-piperidine pinacol ester HCl
EINECS	Contact for details

Quality Control

Our Piperidine-4-Boronic Acid Pinacol Ester Hcl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.