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3-Ethyl-4-Formylphenylboronic Acid CAS NO 1218790-94-3


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CAS No.:1218790-94-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Ethyl-4-Formylphenylboronic Acid is a versatile boronic acid derivative featuring both an aldehyde and an ethyl substituent on the aromatic ring. This bifunctional structure makes it a valuable advanced pharmaceutical intermediate and a critical building block in modern synthetic chemistry, particularly for Suzuki-Miyaura cross-coupling reactions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science sectors who require high-purity, functionalized boronic acids for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other small-molecule therapeutics.
  • Suzuki-Miyaura Cross-Coupling: Serves as a crucial coupling partner for forming carbon-carbon bonds between aromatic rings, enabling the construction of complex biaryl structures.
  • Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and plant growth regulators.
  • Ligand and Catalyst Development: The aldehyde group allows for further functionalization to create novel ligands for catalysis or metal-organic frameworks (MOFs).
  • Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and photovoltaic cells.
  • Chemical Biology Probes: Useful for creating tagged molecules or affinity probes for studying biological processes.

Basic Information

Item Detail
Product Name 3-Ethyl-4-Formylphenylboronic Acid
CAS No. 1218790-94-3
Molecular Formula C9H11BO3
Molecular Weight 177.99 g/mol
Synonyms 4-Formyl-3-ethylbenzeneboronic acid; (4-Formyl-3-ethylphenyl)boronic acid; 3-Ethyl-4-formylbenzeneboronic acid; 3-Ethyl-4-carboxybenzaldehyde boronic acid (tautomer); Boronic acid, B-(4-formyl-3-ethylphenyl)-; 3-Ethyl-4-formylphenyl-B(OH)2
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Quality Control

Our 3-Ethyl-4-Formylphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) to prevent moisture absorption and degradation.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Purity (HPLC) ≥97.0%
Water Content (KF) ≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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