Description

2-Fluorobiphenyl-3-Ylboronic Acid is a high-purity boronic acid derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling precise carbon-carbon bond formation via the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to develop novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key synthon for constructing fluorinated biphenyl scaffolds present in various drug candidates, particularly in kinase inhibitors and CNS-active compounds.
• Agrochemical Synthesis: Used in the research and development of new-generation herbicides and fungicides that incorporate fluorinated aromatic systems for enhanced efficacy and environmental profile.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and organic photovoltaics, where the fluorobiphenyl unit modulates electronic properties.
• Ligand & Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis and as a building block for functionalized porous materials like MOFs and COFs.
• Chemical Biology & Probe Design: Utilized to create fluorinated chemical probes and tags for studying biological processes and protein interactions.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses serving the fine chemical and life science industries.

Basic Information

Product Name	2-Fluorobiphenyl-3-Ylboronic Acid
CAS No.	1218790-57-8
Molecular Formula	C12H10BFO2
Molecular Weight	216.02 g/mol
Synonyms	(3-Borono-2-fluorobiphenyl); 2-Fluoro-3-biphenylboronic Acid; 2-Fluoro[1,1'-biphenyl]-3-boronic Acid; (2-Fluorobiphenyl-3-yl)boronic Acid; B-(2-Fluoro[1,1'-biphenyl]-3-yl)boronic Acid; 3-Borono-2-fluorobiphenyl; [1,1'-Biphenyl]-3-boronic acid, 2-fluoro-; 1218790-57-8
EINECS	Contact for details

Quality Control

Every batch of 2-Fluorobiphenyl-3-Ylboronic Acid is produced and tested under a strict quality management system. We employ advanced analytical techniques including NMR (¹H, ¹³C, ¹⁹F, ¹¹B), HPLC, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage or when opening the primary container to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
NMR Purity (¹H)	≥ 95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.