Description

2-Cyano-3-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxa-Borolan-2-Yl)-Phenyl]-Acrylic Acid Ethyl Ester is a high-value, multi-functional chemical intermediate featuring a boronic ester pinacol group and a cyanoacrylate moiety. This compound matters for its critical role in modern synthetic chemistry, particularly in Suzuki-Miyaura cross-coupling reactions, enabling the efficient construction of complex organic frameworks. It is primarily needed by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates via palladium-catalyzed cross-coupling.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides requiring complex aryl-aryl linkages.
• Material Science Research: Serves as a precursor for organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge transport materials.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands and organometallic catalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized to create tagged molecules and bioconjugates for imaging and diagnostic applications.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for creating specialty polymers with tailored properties.

Basic Information

Product Name	2-Cyano-3-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxa-Borolan-2-Yl)-Phenyl]-Acrylic Acid Ethyl Ester
CAS No.	1218790-51-2
Molecular Formula	C20H26BNO4
Molecular Weight	355.24 g/mol
Synonyms	Ethyl (2E)-2-Cyano-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]prop-2-enoate; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzylidenecyanoacetic Acid Ethyl Ester; (E)-Ethyl 2-Cyano-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)acrylate; 2-Propenoic acid, 2-cyano-3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-, ethyl ester, (2E)-; Boronic acid, B-[4-[(1E)-2-(ethoxycarbonyl)-2-cyanoethenyl]phenyl]-, 4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester; 4-Boronophenyl acrylic acid ethyl ester derivative; Pinacol boronate acrylate ester.
EINECS	Contact for details

Quality Control

Our 2-Cyano-3-[4-(4,4,5,5-Tetramethyl-[1,3,2]Dioxa-Borolan-2-Yl)-Phenyl]-Acrylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent performance in sensitive coupling reactions. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.