Description

4-(Cyclohexyliminomethyl)Benzeneboronic Acid Pinacol Ester is a specialized organoboron compound, specifically a protected boronic acid ester, that serves as a critical synthetic intermediate. Its primary value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are fundamental for constructing complex molecules in modern organic synthesis. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable building blocks for drug discovery and fine chemical production.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those requiring biaryl or substituted aromatic structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage boronic acid chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, ligands for catalysts, and novel polymers where precise aromatic coupling is necessary.
• Chemical Biology & Probe Development: Serves as a precursor for synthesizing molecular probes and bioconjugation reagents used in diagnostic and biochemical research.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aromatic rings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	4-(Cyclohexyliminomethyl)Benzeneboronic Acid Pinacol Ester
CAS No.	1218790-50-1
Molecular Formula	C19H28BNO2
Molecular Weight	313.24 g/mol
Synonyms	4-[(Cyclohexylimino)methyl]benzeneboronic acid pinacol ester; Benzeneboronic acid, 4-[(cyclohexylimino)methyl]-, 1,1-dimethylethyl ester; 4-(N-Cyclohexylformimidoyl)phenylboronic acid pinacol ester; 4-(Cyclohexyliminomethyl)phenylboronic acid pinacol ester; Pinacol [4-(cyclohexyliminomethyl)phenyl]boronate; CAS 1218790-50-1; Boron, [4-[(cyclohexylimino)methyl]phenyl]-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 4-(Cyclohexyliminomethyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.