Description

4-(tert-Butyliminomethyl)Benzeneboronic Acid Pinacol Ester is a specialized organoboron compound, specifically a protected boronic acid derivative, that serves as a critical building block in modern synthetic chemistry. Its core value lies in its enhanced stability and reactivity profile compared to its free boronic acid counterpart, making it a superior reagent for demanding cross-coupling reactions. This high-purity intermediate is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, particularly in creating biaryl and heterobiaryl structures common in active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, enabling the introduction of the phenylboronate moiety into complex molecules.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as those used in OLEDs or organic photovoltaics, due to its conjugated system.
• Ligand and Catalyst Development: Employed in the synthesis of novel ligands for transition metal catalysis or as a component in metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized in the development of molecular probes and sensors that leverage boronate chemistry for selective binding to diols or other biological targets.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	4-(tert-Butyliminomethyl)Benzeneboronic Acid Pinacol Ester
CAS No.	1218790-47-6
Molecular Formula	C₁₇H₂₆BNO₂
Molecular Weight	287.21 g/mol
Synonyms	4-[(tert-Butylimino)methyl]benzeneboronic acid pinacol ester; 4-(tert-Butyliminomethyl)phenylboronic acid pinacol ester; (4-((tert-Butylimino)methyl)phenyl)boronic acid pinacol ester; N-tert-Butyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzimidoyl; Benzaldehyde, 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-, N-(1,1-dimethylethyl)imine
EINECS	Contact for details

Quality Control

Every batch of 4-(tert-Butyliminomethyl)Benzeneboronic Acid Pinacol Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including NMR (¹H, ¹³C, ¹¹B), HPLC, and GC-MS, to ensure identity, purity, and consistency meet the high standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation and maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.