Description

4-(4-Furfuryl)Iminomethyl Phenyl-Boronic Acid Pinacol Ester is a specialized organoboron compound, specifically a protected boronic acid ester, designed for advanced synthetic applications. This high-value intermediate is critical for enabling efficient and selective cross-coupling reactions, such as the Suzuki-Miyaura reaction, which are foundational to modern pharmaceutical and agrochemical development. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to construct complex molecular architectures with precision.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for constructing biaryl and heterobiaryl motifs prevalent in drug candidates.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic coupling steps.
• Material Science Research: Serves as a precursor in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Chemical Biology & Probe Development: Employed in the creation of molecular probes and sensors that utilize boronic acid chemistry for detecting biological analytes.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura cross-coupling to form carbon-carbon bonds between aromatic rings.
• Library Synthesis for Drug Discovery: Enables the rapid, parallel synthesis of diverse compound libraries for high-throughput screening in medicinal chemistry.

Basic Information

Product Name	4-(4-Furfuryl)Iminomethyl Phenyl-Boronic Acid Pinacol Ester
CAS No.	1218790-46-5
Molecular Formula	C18H22BNO3
Molecular Weight	311.19 g/mol
Synonyms	4-[(Furan-2-ylmethyl)iminomethyl]benzeneboronic acid pinacol ester; [4-[[(2-Furanylmethyl)imino]methyl]phenyl]boronic acid pinacol ester; 4-((Furfurylimino)methyl)phenylboronic acid pinacol ester; Pinacol 4-[(furan-2-ylmethylimino)methyl]benzeneboronate; B-[4-[[(2-Furanylmethyl)imino]methyl]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-(4-Furfuryliminomethyl)phenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 4-(4-Furfuryl)Iminomethyl Phenyl-Boronic Acid Pinacol Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and IR spectroscopy. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.