Description

2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-(p-Toluenesulfonyl)-1H-Pyrrole is a high-value, multi-functional organoboron building block, essential for modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, particularly the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is critically needed by pharmaceutical R&D teams, agrochemical innovators, and advanced material scientists for the synthesis of novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing novel drug candidates, especially in heterocyclic chemistry for oncology and CNS targets.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides requiring specific pyrrole-based structures.
• Material Science: Serves as a monomer or cross-linking agent in the development of advanced polymers and organic electronic materials.
• Suzuki-Miyaura Cross-Coupling: The protected boronic ester functionality makes it a stable and reactive partner for palladium-catalyzed C-C bond formation.
• Chemical Research & Development: A versatile reagent for academic and industrial labs exploring new synthetic methodologies and complex molecule construction.
• Ligand and Catalyst Preparation: Used to synthesize specialized ligands for catalysis or as part of catalyst frameworks themselves.

Basic Information

Item	Detail
Product Name	2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-(p-Toluenesulfonyl)-1H-Pyrrole
CAS No.	1218790-43-2
Molecular Formula	C17H24BNO4S
Molecular Weight	349.25 g/mol
Synonyms	1-Tosyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrrole 1-tosylate; 1H-Pyrrole, 2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-[(4-methylphenyl)sulfonyl]-; N-Tosyl-2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrrole; 2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-tosyl-1H-pyrrole; Boric acid, cyclic ester with 1-tosyl-1H-pyrrole-2-boronic acid
EINECS	Contact for details

Quality Control

Our 2-(4,4,5,5-Tetramethyl-1,3,2-Dioxaborolan-2-Yl)-1-(p-Toluenesulfonyl)-1H-Pyrrole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural integrity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.