Description

2-(3-Bromo-5-Propoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane CAS NO 1218790-36-3 is a high-purity boronic ester derivative, a critical building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone of pharmaceutical and advanced material synthesis. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries who require reliable, high-quality intermediates for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides requiring specific phenyl-boronate coupling partners.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as polymers for OLEDs (Organic Light-Emitting Diodes) and OFETs (Organic Field-Effect Transistors).
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts used in asymmetric synthesis and other catalytic processes.
• Chemical Biology & Probe Synthesis: Utilized to create molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-(3-Bromo-5-Propoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1218790-36-3
Molecular Formula	C15H22BBrO3
Molecular Weight	341.05 g/mol
Synonyms	3-Bromo-5-propoxybenzeneboronic acid pinacol ester; (3-Bromo-5-propoxy-phenyl)boronic acid pinacol ester; 2-(3-Bromo-5-propoxy-phenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane; 3-Bromo-5-propoxybenzeneboronic acid, pinacol ester; 3-Bromo-5-propoxy phenylboronic acid pinacol ester; Pinacol (3-bromo-5-propoxy-phenyl)boronate
EINECS	Contact for details

Quality Control

Our 2-(3-Bromo-5-Propoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our commitment to supply chain reliability and documentation transparency supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain optimal stability and purity. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.