Description

2-(3-Bromo-5-Butoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a critical building block in modern synthetic chemistry. Its value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone for constructing complex molecular architectures. This advanced intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional organic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for complex, multi-ring structures.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with specific activity profiles.
• Liquid Crystal & OLED Material Development: Serves as a building block for advanced organic electronic materials requiring specific bromo- and butoxy-substituted phenyl groups.
• Polymer & Specialty Chemical Manufacturing: Enables the incorporation of functional aromatic units into polymers and specialty monomers.
• Academic & Contract Research: A valuable reagent for method development and exploratory synthesis in medicinal and organic chemistry laboratories.

Basic Information

Product Name	2-(3-Bromo-5-Butoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1218790-35-2
Molecular Formula	C16H24BBrO3
Molecular Weight	355.08 g/mol
Synonyms	3-Bromo-5-butoxyphenylboronic acid pinacol ester; (3-Bromo-5-butoxyphenyl)boronic acid pinacol ester; 3-Bromo-5-butoxybenzeneboronic acid pinacol ester; 2-(3-Bromo-5-butoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 1218790-35-2; 5-Butoxy-3-bromophenylboronic acid pinacol ester; 3-Bromo-5-n-butoxyphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our production of 2-(3-Bromo-5-Butoxyphenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for sensitive coupling reactions. Every lot is characterized by advanced analytical techniques including NMR, HPLC, and GC to confirm identity, purity, and the absence of critical impurities like palladium. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to maintain optimal purity and reactivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.